Search results for "Working groups"
showing 6 items of 6 documents
European code against cancer 4th edition: 12 ways to reduce your cancer risk
2015
AbstractThis overview describes the principles of the 4th edition of the European Code against Cancer and provides an introduction to the 12 recommendations to reduce cancer risk. Among the 504.6 million inhabitants of the member states of the European Union (EU28), there are annually 2.64 million new cancer cases and 1.28 million deaths from cancer. It is estimated that this cancer burden could be reduced by up to one half if scientific knowledge on causes of cancer could be translated into successful prevention. The Code is a preventive tool aimed to reduce the cancer burden by informing people how to avoid or reduce carcinogenic exposures, adopt behaviours to reduce the cancer risk, or t…
Loss of life expectancy from air pollution compared to other risk factors: a worldwide perspective
2020
Abstract Aims Long-term exposure of humans to air pollution enhances the risk of cardiovascular and respiratory diseases. A novel Global Exposure Mortality Model (GEMM) has been derived from many cohort studies, providing much-improved coverage of the exposure to fine particulate matter (PM2.5). We applied the GEMM to assess excess mortality attributable to ambient air pollution on a global scale and compare to other risk factors. Methods and results We used a data-informed atmospheric model to calculate worldwide exposure to PM2.5 and ozone pollution, which was combined with the GEMM to estimate disease-specific excess mortality and loss of life expectancy (LLE) in 2015. Using this model, …
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder
2018
Psychiatric disorders are thought to have a complex genetic pathology consisting of interplay of common and rare variation. Traditionally, pedigrees are used to shed light on the latter only, while here we discuss the application of polygenic risk scores to also highlight patterns of common genetic risk. We analyze polygenic risk scores for psychiatric disorders in a large pedigree (n ~ 260) in which 30% of family members suffer from major depressive disorder or bipolar disorder. Studying patterns of assortative mating and anticipation, it appears increased polygenic risk is contributed by affected individuals who married into the family, resulting in an increasing genetic risk over generat…
Introduzione alle relazioni finali dei gruppi
2016
Sono introdotte e commentate le relazioni finali dei gruppi di studio che si sono svolti durante la Summer School organizzata dalla Siped a Enna nel luglio del 2015. I diversi contributi sono collocati all’interno del dibattito scientifico in corso per ognuno dei temi affrontati nei lavori svolti durante la manifestazione sulle tendenze della ricerca pedagogica in Italia. The final reports of the study groups that worked during the Summer School organized by SIPED in Enna in July 2015 are here introduced and discussed. The various contributions are placed within the current scientific debate for each one of the themes dealing with during the demonstration on pedagogical research trends in I…
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis â A EUFOREA-ARIA-EPOS-AIRWAYS IC…
2017
Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging dat…
A Proposal of Process Fragment Definition and Documentation
2012
This paper focuses on the field of Situational Method Engineering (SME) for the construction of agent-oriented design processes. Whatever SME approach a method designer wants to use, he has to manage two main elements: the (method or process) fragment and the repository where it is stored. Specific fragment definition and documentation are fundamental during these activities, for new process composition, and for the consequent system design activities. This paper aims at illustrating a proposal of fragment definition and documentation. This proposal is aimed to be an input for the IEEE FIPA Design Process Documentation and Fragmentation working group and, as regards our own research work, t…